Febrol Side Effects

Febrol is generally considered safe when used as directed, but it can have both common and less common side effects. Here is a breakdown of both.

Common Side Effects

• Nausea and Vomiting: Some individuals may experience nausea and vomiting, especially when taking higher doses of or on an empty stomach of Febrol.
• Digestive Distress: Upset stomach or abdominal discomfort can occur in some people with Febrol.
• Skin Reactions: Febrol can rarely cause skin rashes or itching in some individuals.
• Hypersensitivity Reactions: A mild allergic reaction may occur in some cases, presenting as skin rash or itching.
• Blood Disorders: Febrol can lead to rare blood disorders such as agranulocytosis (severe reduction in white blood cells) or thrombocytopenia (a reduction in platelets).

Less Common Side Effects

• Allergic Reactions: While rare, more severe allergic reactions, such as swelling of the face, tongue, or throat, difficulty breathing, and anaphylaxis, can occur.
• Liver Damage: Febrol can be harmful to the liver when taken in excessive amounts or in cases of overdose, leading to potentially life-threatening liver damage.
• Kidney Damage: Although rare, Febrol has been associated with kidney damage in some cases.
• Gastrointestinal Problems: Some individuals may experience severe stomach pain or bleeding, though this is less common compared to nonsteroidal anti-inflammatory drugs (NSAIDs).
• Severe Skin Reactions: In rare cases, severe skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis can occur.
• Blood Pressure Changes: Febrol has been reported to cause changes in blood pressure, but this is relatively uncommon.
• Neurological Symptoms: Rarely, some individuals may experience neurological symptoms such as confusion or hallucinations.
• Overdose: Taking too much Febrol can lead to an overdose, which is dangerous and potentially fatal. Symptoms of overdose may not be immediately apparent and can include nausea, vomiting, confusion, and jaundice.

Febrol is one of the leading brands of Paracetamol, manufactured and marketed by Barrett Hodgson Pakistan (Pvt) Ltd.

Presently, Febrol is available in Tablet and Suspension Forms

Febrol Tablet : 500mg Strength

Febrol Suspension : 250mg/5ml Strength

1. Alcohol: Drinking alcohol while taking Febrol can increase the risk of liver damage. Both Febrol and alcohol are metabolized by the liver, and combining them can strain the liver.
2. Medications That Affect Liver Enzymes: Some medications, such as those used for the treatment of epilepsy (e.g., carbamazepine) or tuberculosis (e.g., rifampicin), can induce liver enzymes. This may affect the way the liver processes Febrol, potentially reducing its effectiveness or increasing the risk of liver damage.
3. Warfarin: Febrol can interact with warfarin, an anticoagulant (blood thinner). This interaction can increase the risk of bleeding because Febrol may affect how warfarin is metabolized in the body.
4. Other Over-the-counter and Prescription Pain Relievers: Combining Febrol with other pain relievers like nonsteroidal anti-inflammatory drugs (NSAIDs) or opioid medications can increase the risk of side effects or overdose. Make sure to follow dosing instructions and consult a healthcare professional if you are considering such combinations.
5. Medications for High Blood Pressure: Some medications used to treat hypertension, such as angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), may be less effective when used with Febrol.
6. Anti-Seizure Medications: Febrol may interact with anti-seizure medications like phenytoin, which can lead to a reduction in the effectiveness of both the anti-seizure drug and Febrol.
7. Isoniazid: This medication used to treat tuberculosis can increase the risk of liver damage when combined with Febrol.
8. Herbal Supplements: Some herbal supplements, like St. John’s wort, can affect how the liver processes medications, potentially impacting the effectiveness of Febrol.