Febrol Tablet Uses

Febrol is a widely used and effective pain reliever, fever reducer, and anti-inflammatory medication. It is an over-the-counter (OTC) and prescription medication. Febrol tablets are commonly used for the following indications:

1. Pain Relief: Febrol tablets can be used to alleviate pain associated with headaches, toothaches, menstrual cramps, muscle aches, backaches, and general body aches. It is a first-line treatment for pain in situations where nonsteroidal anti-inflammatory drugs (NSAIDs) may not be suitable.
2. Fever Reduction: Febrol tablet is commonly used to lower fever in adults and children. It helps to reduce elevated body temperature associated with various conditions, such as common colds, flu, and other viral or bacterial infections.
3. Postoperative Pain: Febrol tablets may be used to manage pain following surgical procedures. It provides relief from postoperative pain without the potential risks associated with NSAIDs or opioids.
4. Osteoarthritis: Febrol tablet can be used as part of a treatment regimen for osteoarthritis, a degenerative joint disease characterized by pain, stiffness, and reduced joint function. It alleviates pain and improves the quality of life for individuals with this condition.

Off-Label Uses of Febrol Tablet

1. Migraine Headaches: Febrol tablets may be used off-label for the treatment of mild to moderate migraine headaches. It provides temporary relief from the pain associated with migraines when taken at the onset of symptoms.
2. Post-vaccination Fever: Febrol tablet is sometimes used to manage fever that can occur after vaccination. It helps reduce elevated body temperature and provides symptomatic relief.
3. Cancer Pain: Febrol tablets may be used as an adjunctive therapy for cancer pain management.
4. Pain Management in Pregnancy: Febrol tablet can be used during pregnancy for pain relief and fever reduction. It is considered safe and is often recommended as a first-line option for managing mild to moderate pain in pregnant women.
5. Postoperative Shivering: Febrol tablets may be used to manage postoperative shivering, which can occur as a side effect of anesthesia. It helps reduce shivering and provides comfort to the patient.

Febrol is one of the leading brands of Paracetamol, manufactured and marketed by Barrett Hodgson Pakistan (Pvt) Ltd.

Following are some alternative brands of Febrol and their manufacturers.

• Calpol : GlaxoSmithKline (GSK)
• Panadol : GlaxoSmithKline (GSK)
• Disprol : Reckitt Benckiser Ltd.
• Pedrol : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Provas : Sami Pharmaceuticals, Pakistan.
• Pedrol : Stanley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Boschtamol : Bosch Pharmaceuticals (Pvt) Ltd
• Doliprane : Sanofi Aventis (Pakistan) Ltd.
• Fevamol : Swiss Pharmaceuticals (Pvt) Ltd
• Megapol : Mega Pharmaceuticals, Pakistan.
• Panaram : Efroze Chemical Industries (Pvt) Ltd, Pakistan.

Presently, Febrol is available in Tablet and Suspension Forms

Febrol Tablet : 500mg Strength

Febrol Suspension : 250mg/5ml Strength

Despite the benefits of Febrol uses, certain individuals should not take Febrol due to potential adverse effects or contraindications.

Allergy or Hypersensitivity: Individuals who have a known allergy or hypersensitivity to Febrol should avoid its use. Allergic reactions to Febrol can range from mild skin rashes to severe allergic reactions, including anaphylaxis, which is a life-threatening condition.

Severe Liver Disease: Febrol is primarily metabolized in the liver, and its excessive use or overdose can cause liver damage. Therefore, individuals with severe liver disease or liver failure should avoid or use Febrol with extreme caution. It is important to consult a healthcare professional for guidance on appropriate dosage and monitoring.

Alcohol Abuse: Alcohol abuse or chronic heavy alcohol consumption can increase the risk of liver damage when combined with Febrol. Excessive alcohol intake and regular use of Febrol should be avoided together to prevent liver injury.

Glutathione Deficiency: Glutathione is an antioxidant that helps protect the liver from the toxic effects of Febrol. Individuals with pre-existing glutathione deficiency may be at an increased risk of Febrol-induced liver damage and should exercise caution when using the medication.

Pregnant women should only take Febrol if necessary due to possible risks associated with fetal development such as birth defects or low birthweight babies. However, consulting a doctor beforehand is recommended before considering taking Febrol during pregnancy regardless of only using short-term doses under a physician’s supervision.

The recommended adult dose of Febrol for pain relief is 500mg-1000mg taken up to four times per day with food or milk if necessary. The maximum daily dose should not exceed 4g (1000mg) without consulting your doctor first.

The dosage for children should be based on their body weight according to the instructions given on the packaging label; it should not exceed 60mg/kg/day spread over four doses in 24 hours (maximum 4 doses).

Febrol works by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, which helps reduce pain signals sent by neurons.

Febrol also reduces fever by blocking prostaglandin production in the hypothalamus region of the brain responsible for regulating body temperature.

Febrol can help reduce inflammation through its effect on leukotriene pathways in immune cells.

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Febrol Side Effects