Brevoxyl cream is a topical medication used to treat mild to moderate acne. It works by killing the bacteria that cause acne, as well as by drying out the skin and peeling away dead skin cells.

About Brevoxyl Cream

  • Generic Name: Benzoyl Peroxide
  • Properties: Antibacterial and Anti-inflammatory
  • Manufactured and Marketed By: Stiefel Laboratories
  • Presentation: 20gm and 40gm Tube (Cream form)
Brevoxyl Cream Uses and Indications

Common Uses and Indications of Brevoxyl Cream

  1. Acne Treatment: The primary use of Brevoxyl cream is to treat acne. It is effective for both mild and moderate forms of acne. It works by reducing the number of acne-causing bacteria on the skin’s surface and by helping to unclog pores. This can result in a reduction in pimples, whiteheads, blackheads, and inflamed lesions associated with acne.
  2. Acne Prevention: In addition to treating existing acne, Brevoxyl can also be used to prevent new acne breakouts. Some people use it as a maintenance treatment to keep their skin clear after their acne has improved.
  3. Keratolytic Agent: Brevoxyl acts as a keratolytic, which means it helps to break down and remove dead skin cells. This can be particularly helpful in preventing clogged pores, which are a common precursor to acne.
  4. Complementary Therapy: Brevoxyl is often used in combination with other acne treatments, such as topical antibiotics or retinoids. These combinations can provide a more comprehensive approach to acne management by targeting different aspects of the condition, such as bacteria and inflammation.
  5. Treatment for Other Skin Conditions: In some cases, Brevoxyl may be used to treat other skin conditions, such as folliculitis (inflammation of hair follicles) or perioral dermatitis (a rash around the mouth).

Off-label Uses of Brevoxyl Cream

  1. Folliculitis: Brevoxyl cream’s antibacterial properties may make it effective in treating folliculitis, which is the inflammation of hair follicles often caused by bacterial or fungal infections. It may help reduce the infection and associated symptoms.
  2. Rosacea: Some individuals with rosacea, a chronic skin condition characterized by redness, flushing, and sometimes acne-like bumps, may benefit from Brevoxyl cream. It can help manage the acne component of rosacea, but it should be used cautiously and under the guidance of a dermatologist as it can be irritating to sensitive skin.
  3. Seborrheic Dermatitis: Brevoxyl cream may be used off-label to manage seborrheic dermatitis, a common skin condition that causes redness, scaling, and itching, especially in areas rich in oil glands like the scalp, face, and chest. It can help reduce excess oil and flaking associated with the condition.
  4. Ingrown Hairs: Some people use Brevoxyl cream to help prevent and treat ingrown hairs, especially in areas where hair removal methods like shaving or waxing are common. It can reduce inflammation and prevent hair follicles from becoming clogged.
  5. Hyperpigmentation: In some cases, Brevoxyl cream may be used off-label to treat post-inflammatory hyperpigmentation (PIH) that can occur after acne breakouts. By helping to clear acne lesions, it may indirectly reduce the risk of PIH.

Formulation and Ingredients

  • Benzoyl Peroxide: 4%w/w

Benzoyl Peroxide Concentration: The concentration of Benzoyl Peroxide in the cream can vary. Lower concentrations (2.5% to 5%) are suitable for mild acne, while higher concentrations (up to 10%) may be necessary for more severe cases. It’s essential to start with a lower concentration and gradually increase if needed.

How to Apply Brevoxyl Cream

  • Patch Testing: Before applying Brevoxyl cream to your entire face, it’s advisable to conduct a patch test. Apply a small amount to a discreet area to check for any adverse reactions or allergies.
  • Daily Application: For optimal results, apply the cream once a day, usually in the evening, after cleansing your face. Avoid excessive use, as it can lead to dryness and irritation.
  • Moisturizing and Sunscreen: Due to its drying effect, it’s crucial to moisturize your skin regularly when using Brevoxyl. Additionally, always wear sunscreen during the day to protect your skin from UV damage.

Who Should Avoid Brevoxyl Cream? – Contraindications

  1. Allergy or Hypersensitivity: If you have a known allergy or hypersensitivity to Benzoyl Peroxide or any of the ingredients in the cream, you should not use it. Allergic reactions can range from mild skin irritation to more severe symptoms like itching, swelling, or hives.
  2. Skin Sensitivity: Individuals with very sensitive or easily irritated skin should use Brevoxyl with caution. It can be drying and may cause redness, peeling, and irritation, especially when first used. Lower concentrations (2.5% or 5%) are often recommended for individuals with sensitive skin.
  3. Skin Conditions: Avoid using Brevoxyl cream on areas of the skin that are sunburned, windburned, chapped, or excessively dry. It may exacerbate these conditions and cause more irritation.
  4. Pregnancy and Breastfeeding: While Brevoxyl cream is generally considered safe for use during pregnancy and breastfeeding when used topically, it’s essential to consult a healthcare provider before using any medication during these periods. They can provide guidance on the safest options for your specific situation.
  5. Children: Brevoxyl cream use in children under the age of 12 is typically not recommended unless directed by a healthcare provider. Children may have more sensitive skin, and alternative treatments may be preferred.
  6. Combination with Certain Medications: Brevoxyl cream may interact with certain topical or oral medications. For example, using it in combination with topical tretinoin (a retinoid) may increase skin irritation. It’s crucial to inform your healthcare provider about all medications and products you are using to avoid potential interactions.
  7. Medical Conditions: If you have underlying medical conditions affecting your skin or if you are taking medications for other skin conditions, discuss the use of Brevoxyl cream with your healthcare provider. Certain skin conditions may be aggravated by Brevoxyl.
  8. Sun Exposure: Brevoxyl cream can make the skin more sensitive to the sun’s ultraviolet (UV) rays. If you use Brevoxyl, be diligent about applying sunscreen daily to protect your skin from sun damage.

FAQs

  1. Q: Is Brevoxyl cream cream suitable for all skin types?
    No, it is best for acne-prone and oily skin types. Those with sensitive or dry skin should use it with caution.
  2. Q: Can I use Brevoxyl cream with other acne treatments?
    Yes, but be careful when combining it with other potent treatments, as it may increase skin sensitivity.
  3. Q: How long does it take to see results with Brevoxyl cream?
    Results can vary, but many people notice an improvement in their acne within a few weeks of consistent use.
  4. Q: Are there any alternatives to Brevoxyl cream for acne treatment?
    Yes, alternatives include salicylic acid, sulfur, and topical antibiotics. Consult with a dermatologist to find the best option for you.
  5. Q: Is it safe to use Brevoxyl cream during pregnancy?
    It’s advisable to consult with a healthcare provider before using any skincare products containing Benzoy.

Brevoxyl cream’s Alternatives : Other Similar Brands

The following are Some alternative brands of Brevoxyl Cream and their manufacturers.

Crozyl : AGP (Pvt) Ltd, Pakistan.

Oxyzole : Valor Pharmaceuticals, Pakistan.

Aknekream : Werrick Pharmaceuticals, Pakistan.

Benoxyl : Glitz Pharma, Pakistan.

Benzagel : Pharma Health Pakistan (Pvt) Ltd.

Benzo : Wise Pharmaceuticals (Pvt) Ltd, Pakistan.

Cara-Benz : Caraway Pharmaceuticals, Pakistan.

Li-Ben : Liner Pharma, Pakistan.