Terbisil cream is a topical medication that belongs to a class of antifungal drugs called allylamines. It is used to treat various fungal skin infections, primarily those caused by dermatophytes, which are fungi that can infect the skin, hair, and nails. The following are some common uses and indications of Terbisil Cream:

  1. Athlete’s Foot (Tinea Pedis): Terbisil cream is commonly used to treat athlete’s foot, a fungal infection that affects the feet, especially the spaces between the toes. Symptoms of an athlete’s foot can include itching, redness, peeling, and discomfort.
  2. Ringworm (Tinea Corporis): Ringworm is a fungal infection that appears as a circular or ring-like rash on the skin. Terbisil cream can be used to treat ringworms on various parts of the body.
  3. Jock Itch (Tinea Cruris): Jock itch is a fungal infection that affects the groin area, including the inner thighs and genital region. Terbisil cream can help relieve the symptoms of itching, redness, and irritation associated with jock itch.
  4. Candidiasis (Yeast Infections): Although Terbisil is primarily effective against dermatophytes, it may also have some activity against certain yeast species. Terbisil cream might be used in cases of cutaneous candidiasis, a fungal infection caused by Candida yeast.
  5. Fungal Nail Infections (Onychomycosis): While Terbisil cream is primarily used for topical fungal infections, Terbisil is also available in oral form and is commonly prescribed for treating fungal nail infections (onychomycosis).
  6. Fungal Infections of the Body: Terbisil cream can also be used to treat other fungal infections of the body caused by dermatophytes.
  7. Fungal Infections of the Hands: Infections caused by dermatophytes on the hands, known as tinea manuum, can be treated with Terbisil cream.
  8. Fungal Infections of the Face: Fungal infections of the face, known as tinea faciei, can be treated with Terbisil cream under medical supervision.
  9. Fungal Infections in Children: Terbisil cream may be used to treat fungal infections in children, especially those that affect the feet, body, or groin area.

Off-label Uses of Terbisil Cream

  1. Tinea Versicolor: Tinea versicolor is a fungal skin infection caused by Malassezia yeasts. While Terbisil is not commonly used to treat this condition, there have been cases where it was used off-label as an alternative treatment option.
  2. Mild Eczema: In some cases, Terbisil cream might be used off-label to help alleviate itching and discomfort associated with mild eczema, although corticosteroid creams are typically the primary choice for eczema treatment.
  3. Fungal Diaper Rash: Terbisil cream might be considered off-label for treating fungal diaper rash, especially if other antifungal options are not available or suitable.
  4. Folliculitis: Folliculitis is an infection or inflammation of hair follicles. In cases where the infection is caused by fungi, Terbisil cream might be used off-label to address the fungal component of the condition.
  5. Intertrigo: Intertrigo is a skin condition that occurs in areas where skin rubs against the skin, creating a warm and moist environment that can lead to infections. Terbisil cream might be considered off-label for intertrigo caused by fungal infections.
  6. Prophylactic Use: In some cases, healthcare providers might consider using Terbisil cream off-label as a preventive measure in situations where there is a high risk of fungal infection, such as in individuals with compromised immune systems.
Terbisil Cream Uses and Indications

What is Terbisil?

Terbisil is one of the leading brands of Terbinafine, manufactured and marketed by Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.

Terbisil Alternatives : Terbinafine Other Brands

The following are Some alternative brands of Terbisil Cream and their manufacturers.

Terbiderm : Atco Laboratories (Pvt) Ltd, Pakistan.

Lamisil : GalxoSmithKline (GSK) Pakistan

Cutis : Tabros Pharma, Pakistan.

Terbisan : Sante (Pvt) Ltd, Pakistan.

Fungi-Rid : Bio Labs, Pakistan.

Docinaf : Paramount Pharmaceuticals, Pakistan.

Exinofin : Brookes Pharmaceutical Laboratories (Pakistan) Ltd.

Qtec : Sharooq Pharmaceuticals, Pakistan.

Terabin : Mass Pharma (Pvt) Ltd, Pakistan.

Terbin : Martin Dow Pharmaceuticals (Pvt) Ltd, Pakistan.

Terbisil : Available Formulations and Strengths

Presently, Terbisil is available in Cream and Tablet forms.

Terbisil Cream 10gm Cotains:

  • Terbinafine HCl B.P : 1% w/w

Each Terbisil Tablet Contains:

  • Terbinafine HCl B.P : 125mg

Who Should Not Use Terbisil?

Terbisil cream, like any medication, has specific contraindications – situations or conditions in which its use is not recommended due to potential risks or interactions.

  1. Allergy: If you have a known allergy to terbinafine or any of the ingredients in the cream, you should not use Terbisil cream.
  2. Pregnancy and Breastfeeding: While topical Terbisil is generally considered safe for pregnant or breastfeeding individuals, it’s advisable to consult a healthcare professional before using it during pregnancy or while breastfeeding.
  3. Children and Infants: The use of Terbisil cream in very young children or infants should be done under the guidance of a healthcare professional. Infants have sensitive skin, and caution is needed to prevent irritation.
  4. Severe Skin Conditions: In some cases, using Terbisil cream on skin with conditions like severe burns, open wounds, or other skin disorders could potentially exacerbate the condition or interfere with wound healing.
  5. Immunosuppression: If you have a compromised immune system due to medical conditions or medications (such as immunosuppressive drugs), using Terbisil cream might warrant extra caution and monitoring.
  6. Liver Disease: Terbisil is metabolized in the liver. If you have a history of liver disease or significant liver impairment, using Terbisil cream should be done with careful consideration and under medical supervision.
  7. Use in Eyes, Mouth, or Ears: Terbisil cream is intended for external use only. It should not be used in or around the eyes, mouth, or ears. If the cream comes into contact with these areas, it should be thoroughly rinsed off with water.

How to Use Terbisil Cream?

Terbisil cream once or twice a day for 1-2 weeks.

Here are the steps on how to apply Terbisil cream:

  • Wash your hands thoroughly with soap and water.
  • Dry the affected area of the skin.
  • Apply a thin layer of cream to the affected area.
  • Rub the cream in gently until it is absorbed.
  • Avoid using excessive amounts of cream.
  • After applying avoid covering the affected area.
  • Wash your hands again after applying the cream.

How Terbisil Works?

Terbisil cream is a topical antifungal medication that works by killing the fungus that causes the infection. It does this by interfering with the fungus’s ability to produce ergosterol. Ergosterol is a type of sterol that is essential for the fungus’s cell membrane. Without ergosterol, the fungus’s cell membrane becomes leaky and the fungus dies.