Ulsanic Syrup Uses

Ulsanic syrup is a medication that is primarily used to treat and prevent ulcers in the gastrointestinal (GI) tract. It is also used to prevent stress ulcers, which can occur in people who are under a lot of stress. The following are some common uses and indications of Ulsanic Syrup:

1. Peptic Ulcers: Ulsanic syrup is often used for the treatment of peptic ulcers, including gastric ulcers (in the stomach) and duodenal ulcers (in the first part of the small intestine). It forms a protective barrier over the ulcers, shielding them from stomach acid, digestive enzymes, and other irritants, thereby promoting healing.
2. Gastroesophageal Reflux Disease (GERD): Ulsanic syrup may be used as adjunctive therapy in GERD to help alleviate symptoms and protect the esophagus from further damage caused by stomach acid.
3. Gastritis: Ulsanic syrup can be used to manage and relieve symptoms of gastritis, which is inflammation of the stomach lining. It coats the stomach lining and provides a protective barrier against stomach acid.
4. Esophagitis: In cases of esophagitis (inflammation of the esophagus), Ulsanic syrup can be used to reduce discomfort, protect the esophageal lining, and promote healing.
5. Preventing Ulcers: Ulsanic syrup may be used as a preventive measure in individuals who are at high risk of developing ulcers, such as those taking nonsteroidal anti-inflammatory drugs (NSAIDs) or individuals with a history of ulcers.

Off-label Uses of Ulsanic Syrup

1. Radiation Esophagitis: Ulsanic syrup may be used off-label to manage radiation esophagitis, which is inflammation of the esophagus caused by radiation therapy. It can help relieve symptoms and promote healing by forming a protective coating over the damaged esophageal lining.
2. Chemotherapy-Induced Mucositis: Mucositis is inflammation and ulceration of the mucous membranes, commonly occurring as a side effect of certain chemotherapy medications. Ulsanic syrup may be used off-label to alleviate symptoms and provide a protective barrier to the affected mucous membranes.
3. Laryngopharyngeal Reflux (LPR): LPR is a condition where stomach acid backs up into the throat, leading to irritation and inflammation. Some healthcare providers may prescribe Ulsanic syrup off-label as an adjunctive therapy to help protect the throat and reduce symptoms.
4. Oral Ulcers: Although Ulsanic is primarily used for GI ulcers, there have been reports of its off-label use in the form of a mouth rinse or suspension for the treatment of oral ulcers, such as aphthous ulcers or oral mucositis.

Ulsanic Syrup is one of the leading brands of Sucralfate in oral liquid form, manufactured and marketed by Highnoon Laboratories Ltd, Pakistan.

The following are some alternative brands of Ulsanic Syrup and their manufacturers.

• Surlka : Searle Pakistan (Pvt) Ltd.
• Crafilm : Pacific Pharmaceuticals Ltd, Pakistan.
• Ulcocid : Don Valley Pharmaceuticals (Pvt) Ltd, Pakistan.
• Cytozole : Safe Pharmaceutical (Pvt) Ltd, Pakistan.
• Sucralan : Paramount Pharmaceuticals, Pakistan.
• Cidifen : Libra Pharmaceuticals (Pvt) Ltd, Pakistan.
• Dyfate : Dyson Research Laboratories, Pakistan.
• Medgel : Medicraft Pharmaceuticals (Pvt) Ltd, Pakistan.
• Ulcerate : Helix Pharma (Pvt) Ltd, Pakistan.
• Sucfate : Siza International (Pvt) Ltd, Pakistan.

Presently, Ulsanic is available in Syrup and Tablet forms.

Ulsanic Syrup: 1g/5ml strength.

Ulsanic Tablet: 500mg and 1g strength.

Ulsanic syrup has a few contraindications, which are specific situations or conditions in which the use of Ulsanic is not recommended due to the potential risks outweighing the benefits.

Allergy or Hypersensitivity: Individuals who have a known allergy or hypersensitivity to Ulsanic or any of its components should not use Ulsanic syrup. Allergic reactions can range from mild skin rashes to severe reactions, including difficulty breathing or anaphylaxis.

Renal Impairment: In cases of severe renal impairment or end-stage renal disease, Ulsanic syrup should be used with caution. This is because Ulsanic can be partially absorbed by the body and may accumulate in individuals with impaired kidney function, leading to potentially adverse effects.

Gastrointestinal Obstruction: Ulsanic syrup should not be used in individuals with known or suspected gastrointestinal obstruction. The medication may delay the passage of food and may worsen the obstruction.

Incompatibility with Other Medications: Ulsanic can interact with certain medications, reducing their effectiveness. Therefore, it is important to inform your healthcare professional about all the medications you are taking to determine if any potential interactions exist.

Pediatric Use: The safety and effectiveness of Ulsanic syrup in infants below one year of age have not been established. Therefore, it is generally not recommended for use in this age group.

Ulsanic Syrup Dose for Duodenal Ulcers:

• Adults:1 gram (5 ml of the syrup) four times a day, taken on an empty stomach (at least 1 hour before meals or 2 hours after meals) and at bedtime.

Ulsanic Syrup Dose for Gastric Ulcers:

• Adults: 1 gram (5 ml of the syrup) four times a day, taken on an empty stomach (at least 1 hour before meals or 2 hours after meals) and at bedtime.

Ulsanic Syrup Dose for Maintenance Therapy:

• Adults: 1 gram (5 ml of the syrup) twice a day, taken on an empty stomach (at least 1 hour before meals or 2 hours after meals) and at bedtime.

Ulsanic Syrup Dose for Stress Ulcer:

• 1 gram (5 ml of the syrup), four times a day, taken 1 hour before meals and at bedtime

Ulsanic Syrup Dose for Mucositis:

• 1 gram, four times a day, taken 1 hour before meals and at bedtime

Ulsanic Syrup Dose for Esophagitis:

• 1 gram (5 ml of the syrup), four times a day, taken 1 hour before meals and at bedtime

Ulsanic Syrup Dose for Reflux Esophagitis:

• 1 gram (5 ml of the syrup), four times a day, taken 1 hour before meals and at bedtime

Ulsanic is a medication that acts locally in the gastrointestinal (GI) tract to form a protective coating over ulcers and damaged mucous membranes. Its mode of action involves several mechanisms:

Mucosal Protection: Ulsanic has a unique mechanism of action that involves binding to the damaged mucosa in the GI tract, including ulcers. It forms a complex with the proteins in the exposed tissue, creating a physical barrier or “protective coat.” This barrier helps shield the underlying tissue from gastric acid, bile salts, digestive enzymes, and other irritants that can further damage the ulcers or inflamed areas.

Enhancement of Mucosal Defense Mechanisms: Ulsanic also stimulates the production of substances that promote the healing and protection of the GI mucosa. It increases the synthesis of prostaglandins, which are important for maintaining the integrity of the mucosal lining and promoting blood flow to the damaged areas.

Promotion of Epithelial Cell Growth: Ulsanic has been shown to stimulate the growth of new epithelial cells, which are the cells that line the GI tract. This promotes the regeneration and repair of the damaged mucosal lining, aiding in the healing process of ulcers and other injuries.