Deslor Tablet Use

Deslor tablet is an antihistamine medication used to treat allergic rhinitis and chronic idiopathic urticaria. It belongs to the class of second-generation antihistamines, which are known for being less sedating compared to first-generation antihistamines. Following are some common and off-label uses of Deslor Tablet:

Common Uses of Deslor Tablet

1. Allergic Rhinitis: Deslor tablet is used to alleviate symptoms of allergic rhinitis, including sneezing, runny nose, nasal congestion, and itching of the nose or eyes. Allergic rhinitis is caused by an allergic reaction to substances such as pollen, dust mites, pet dander, or mold spores.
2. Chronic Idiopathic Urticaria: Deslor tablet is also used for the treatment of chronic idiopathic urticaria, a condition characterized by the development of hives (raised, itchy skin) that persist for more than six weeks without an identifiable cause. Desloratadine helps relieve itching and reduces the number and size of hives in individuals with this condition.

Off-label Uses of Deslor Tablet

1. Chronic Pruritus (Itching): Deslor tablets may be used off-label to alleviate chronic itching in conditions such as atopic dermatitis, eczema, and pruritus associated with liver disease. It can help reduce the intensity and frequency of itching.
2. Allergic Conjunctivitis: While Deslor tablet is primarily indicated for allergic rhinitis, it may also be used off-label to alleviate symptoms of allergic conjunctivitis, which involves itching, redness, and watering of the eyes due to an allergic reaction.
3. Mastocytosis: Deslor tablets may be used to reduce symptoms associated with mastocytosis, a condition characterized by an overgrowth of mast cells in various tissues. It can help relieve symptoms such as itching, flushing, and gastrointestinal discomfort.
4. Eosinophilic Esophagitis: Deslor tablets may have a beneficial effect in reducing symptoms associated with eosinophilic esophagitis, an allergic condition that affects the esophagus. It helps alleviate swallowing difficulties, heartburn, and chest pain in some individuals.
5. Dermatographism: Deslor tablets may be used off-label for the treatment of dermatographism, a skin condition characterized by the formation of raised red welts when the skin is scratched or rubbed. It can help reduce the intensity and duration of the skin reaction.

Deslor is one of the leading brands of Desloratadine, manufactured and marketed by Everest Pharmaceuticals, Pakistan.

The following are some alternative brands of Deslor and their manufacturers.

• Desora : Continental Pharmaceuticals, Pakistan.
• Jardin-D : High-Q Pharmaceuticals (Pvt) Ltd, Pakistan.
• Deslavid : Abbott Laboratories, Pakistan.
• Dictrin : Barrett Hodgson Pakistan (Pvt) Ltd.
• Neo-Antial : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Larinex : Getz Pharmaceuticals (Pvt) Ltd, Pakistan.
• Deslet : Efroz Pharmaceuticals (Pvt) Ltd, Pakistan.
• Antimin-D : Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.
• Destina : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Desgen : Envoy Pharmaceuticals (Pvt) Ltd, Pakistan.

Presently, Deslor is available in Tablet Form.

Deslor Tablet : 5mg strength.

Deslor has a few contraindications, meaning there are certain situations where the use of Deslor is not recommended due to potential risks.

1. Hypersensitivity or allergy: Deslor should not be used in individuals who have a known hypersensitivity or allergy to Deslor or any other components of the medication. Allergic reactions can range from mild skin rash to severe anaphylaxis, which is a life-threatening allergic reaction.
2. End-stage renal disease: Deslor is not recommended for individuals with end-stage renal disease (ESRD) who are undergoing hemodialysis. The use of Deslor in these individuals has not been adequately studied, and the medication may accumulate in the body due to impaired kidney function.

1. Deslor Dose for Adults and Children 12 Years and Older:
   • Allergic rhinitis: One Tablet of 5mg, once daily.
2. Deslor Dose for Children 6 to 11 Years:
   • Allergic rhinitis: The recommended dose is 2.5 mg (half a tablet) once daily.

Deslor works by binding to specific receptors called H1 receptors, which are present in various tissues, including blood vessels, respiratory tract, and skin. By selectively binding to and blocking these H1 receptors, Deslor prevents histamine from exerting its effects (allergic reactions).