Brexin Tablet Uses

Brexin tablet is used to reduce fever and swelling from injuries or other medical conditions. It is a non-steroidal anti-inflammatory drug that is used to reduce pain and inflammation in the body. Following are some common and off-label uses of Brexin Tablet:

Common Uses of Brexin Tablet

1. Pain Relief: Brexin tablet is used to relieve pain associated with various conditions, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, menstrual cramps, and dental pain.
2. Inflammatory Conditions: Brexin tablet is used to reduce inflammation associated with various conditions, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and bursitis.
3. Fever Reduction: Brexin tablet is used to reduce fever in individuals with fever associated with various conditions, such as influenza, colds, and other viral infections.
4. Dysmenorrhea: Brexin tablet is used to relieve the pain associated with dysmenorrhea, which is a painful menstrual cramp.
5. Migraine: Brexin tablet is used to relieve the pain associated with migraine headaches.

Off-Label Uses of Brexin Tablet

1. Alzheimer’s Disease: Brexin tablets are used off-label to treat Alzheimer’s disease. It may help reduce inflammation in the brain and improve cognitive function in individuals with Alzheimer’s disease.
2. Cancer: Brexin tablet is also used for certain types of cancer, such as bladder cancer, ovarian cancer, and skin cancer. It may help reduce inflammation and inhibit the growth of cancer cells.
3. Asthma: Brexin tablets may be used off-label to treat asthma. It may help reduce inflammation in the airways and improve breathing in individuals with asthma.

Brexin is one of the leading brands of Piroxicam Beta Cyclodextrin, manufactured and marketed by Chiesi.

The following are some alternative brands of Brexin and their manufacturers.

• Feldene : Pfizer Laboratories Inc.
• NYSA : Getz Pharmaceuticals ( Pvt) Ltd, Pakistan.
• Cyclodex : Platinum Pharmaceuticals ( Pvt) Ltd, Pakistan.
• Pirexin : Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.
• Pytex : High-Q Pharmaceuticals (Pvt) Ltd, Pakistan.
• Boshcam B : Bocsh Pharmaceuticals ( Pvt) Ltd, Pakistan.
• Briax : AGP Pharma, Pakistan.
• Bexagen : Genesis Pharmaceuticals, Pakistan.
• Felbex : Martindow, Pakistan.
• Antixin : Bio-Labs (Pvt) Ltd, Pakistan.

Presently, Brexin is available in Tablet form

Brexin Tablet : 20mg strength

Brexin is a powerful NSAID that can provide relief from pain and inflammation when taken correctly under medical supervision. However, there are some important contraindications that should be considered before using the Brexin tablets.

• People with kidney disease should not take Brexin because it can damage their kidneys over time if they take too much or take it too often.
• Women who are pregnant or breastfeeding should not take Brexin because it may harm the fetus or baby if passed through breast milk during the lactation period.
• People who have had recent heart attacks should also avoid taking this medication due to its potential risks to the cardiovascular system.
• People with allergies to aspirin, ibuprofen, naproxen, ketoprofen, diflunisal, and indomethacin should not use Brexin since these medicines are similar chemically as well as their effects on the body.
• People suffering from any kind of bleeding disorder must consult their doctor before taking Brexin tablets.
• Individuals who have had gastrointestinal problems such as ulcers in the past must inform their physician before taking Brexin tablets.
• This will help them decide whether they need additional tests before beginning treatment with Brexin.

Brexin Tablet Dose for Osteoarthritis and Rheumatoid Arthritis:

• One tablet of 20mg once daily.
• In some cases, a lower initial dose of 10mg (a half tablet) may be recommended.
• Your doctor may adjust the dosage based on your response and tolerance.
• The daily dosage should not exceed 20mg.

Brexin Tablet Dose for Ankylosing Spondylitis:

• One tablet of 20mg once daily.
• The daily dosage should not exceed 20 mg.

Brexin Tablet Dose for Acute Pain and Dysmenorrhea:

• One tablet of 20mg is often taken once daily.
• After the first day, if necessary, the dose may be reduced to 10mg (a half tablet) once daily.
• The total daily dosage should not exceed 20 mg.

Important Note: It is recommended to take Brexin with food to avoid GI side effects.

Brexin like other NSAIDs works by inhibiting the enzymes cyclooxygenases (Cox-1 and -2) resultantly, preventing the synthesis process of prostaglandins, which are responsible for causing pain and inflammation.

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