Cytopan Tablet Uses

Cytopan is primarily used to treat pain and inflammation without causing gastrointestinal problems. Some Common Uses of Cytopan Tablet:

1. Rheumatoid Arthritis: Cytopan tablet is used for the relief of signs and symptoms of rheumatoid arthritis, including joint pain, swelling, and stiffness.
2. Osteoarthritis: Cytopan tablet is used for the management of osteoarthritis, a degenerative joint disease that causes joint pain and stiffness.
3. Ankylosing Spondylitis: Cytopan tablet is also used for the treatment of other types of arthritis, such as ankylosing spondylitis, which primarily affects the spine and sacroiliac joints.
4. Painful Conditions: Cytopan tablets can be used to alleviate pain associated with acute musculoskeletal conditions, such as strains, sprains, and tendonitis.
5. Long-term Uses of NSAIDs: Using Cytopan tablets helps reduce the risk of developing ulcers in individuals who require long-term NSAID therapy. Cytopan’s protective properties on the stomach lining help mitigate the risk of ulcers along with relieving the pain.

Off-label Uses of Cytopan Tablet

1. Juvenile Idiopathic Arthritis: Cytopan tablets may be used off-label in the treatment of juvenile idiopathic arthritis, a type of arthritis that affects children and adolescents.
2. Chronic Pain: Cytopan tablets might be used for the management of chronic pain conditions, such as chronic back pain or chronic musculoskeletal pain.
3. Postoperative Pain: Cytopan tablets can be used to relieve postoperative pain, particularly after orthopedic surgeries or other procedures.
4. Dysmenorrhea: Dysmenorrhea, which refers to painful menstrual cramps, may be treated with Cytopan.
5. Acute Gouty Arthritis: Cytopan tablets may be used in the treatment of acute gouty arthritis, a painful condition caused by the buildup of uric acid crystals in the joints.

Cytopan is one of the leading brands with a combination of Diclofenac Sodium and Misoprostol, manufactured and marketed by Getz Pharmaceuticals (Pvt) Ltd, Pakistan.

Following are some alternative brands of Cytopan and their manufacturers.

• Dyclo-M : Indus Pharmaceuticals, Pakistan.
• Sofac-M : Saffron Pharmaceuticals, Pakistan.
• Rotec : Searl (Pakistan) Ltd.
• Arthrotec : Pfizer Laboratories Ltd.
• Miso Plus : Global Pharmaceuticals, Pakistan.
• Erwin : Sami Pharmaceuticals, Pakistan.
• Esmart : Pharmevo (Pvt) Ltd. Pakistan
• Proart : Bosch Pharmaceuticals, Pakistan.
• Diclotol : Sante (Pvt) Ltd. Pakistan
• Distol : Standpharm Pakistan (Pvt) Ltd.

Presently, Cytopan is available in Tablet Form.

Cytopan Tablet : Diclofenac (Na) 50mg and Misoprostol 200mcg strengths

Despite the potential benefits of Cytopan uses discussed above, there are several contraindications that must be taken into consideration before beginning a course of treatment.

Allergy or Hypersensitivity: Individuals who have a known allergy or hypersensitivity to diclofenac, misoprostol, or any other prostaglandin analogs should not use Cytopan.

Pregnancy: Cytopan is contraindicated during pregnancy. Misoprostol, one of the components of the medication, can cause uterine contractions and potentially lead to abortion or fetal harm. It should not be used in pregnant women or in women who may become pregnant.

History of Asthma or Aspirin Sensitivity: Individuals with a history of asthma, nasal polyps, or other allergic reactions after taking aspirin or other NSAIDs may have an increased risk of experiencing an allergic reaction or exacerbation of asthma symptoms with Cytopan.

Active Peptic Ulcer Disease: Cytopan is contraindicated in individuals with active peptic ulcer disease or a history of gastrointestinal bleeding or perforation. The use of Cytopan can increase the risk of gastrointestinal adverse effects, including bleeding and ulcers.

Severe Renal or Hepatic Impairment: Cytopan is contraindicated in individuals with severe renal or hepatic impairment, as the medication can further compromise kidney and liver function.

Inflammatory Bowel Disease: Cytopan is contraindicated in individuals with inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis, as it may exacerbate the symptoms of these conditions.

Cytopan Dose for Rheumatoid Arthritis:
one tablet 2-4 times daily.
The maximum daily dose should not exceed four tablets of Cytopan a day.

Cytopan Dose for Osteoarthritis:
one tablet 2-4 times daily.
The maximum daily dose should not exceed four tablets of Cytopan a day.

Cytopan combines two active ingredients with distinct modes of action. Here’s a breakdown of how each component works:

Diclofenac Sodium (NSAID): Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the activity of cyclooxygenase (COX) enzymes. These enzymes are responsible for the production of prostaglandins, which are substances involved in the inflammatory response. By inhibiting COX enzymes, diclofenac sodium reduces the production of prostaglandins, leading to decreased inflammation, pain relief, and reduced fever.

Misoprostol (Prostaglandin Analog): Misoprostol is a synthetic prostaglandin E1 analog. It acts by binding to specific receptors on the smooth muscle cells of the gastrointestinal tract, preventing acid secretions and protecting the mucosal layers.

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