Kempro Tablet Uses

Kempro tablet is primarily used for the treatment of Parkinson’s disease, a progressive neurodegenerative disorder that affects movement, coordination, and balance. It belongs to a class of drugs known as anticholinergics. Following are some common and off-label uses of Kempro Tablets:

Common Uses of Kempro Tablet

1. Parkinson’s Disease: Kempro tablet is commonly used in combination with levodopa (a medication that helps replace dopamine in the brain) to manage the symptoms of Parkinson’s disease, including tremors, muscle stiffness, and difficulty with movement.
2. Acromegaly: Kempro tablets can be used in acromegaly, it is a hormonal imbalance condition in which the body starts producing an excessive amount of hormones, that cause muscle and bones to grow abnormally. This condition usually occurs in adults aged 30 to 50 years.
3. Extrapyramidal Symptoms: Kempro tablet can also be used to treat extrapyramidal symptoms (EPS), which are a group of side effects that can occur as a result of taking antipsychotic medications. EPS can include muscle stiffness, tremors, restlessness, and other movement-related problems. By blocking the action of acetylcholine in the brain, Kempro can help alleviate these symptoms.
4. Drug-induced Dystonia: Kempro tablet can be used to treat dystonia, a movement disorder that can be caused by certain medications or other underlying conditions. It helps to reduce muscle spasms and improve motor function by blocking the action of acetylcholine in the brain.

Off-label Uses of Kempro Tablet

Kempro tablets may be used off-label to treat other conditions, such as:

• Drooling
• Excessive Sweating
• Certain Types of Seizures.

Kempro is one of the leading brands of Procyclidine HCl, manufactured and marketed by Adamjee Pharmaceuticals (Pvt) Ltd, Pakistan.

Following are some alternative brands of Kempro and their manufacturers.

• Kemadrin : GlaxoSmithKline (GSK).
• Procye : Glitz Pharma, Pakistan.
• Cyclidine : Pharedic (Pvt) Ltd, Pakistan.
• Epsent : Genetics Pharmaceuticals (Pvt) Ltd, Pakistan.
• Procholidin : Zafa Pharmaceutical Laboratories (Pvt) Ltd.
• Procyclidine : Werrick Pharmaceuticals, Pakistan.
• Xprodine : Mass Pharma (Pvt) Ltd, Pakistan.
• Zyclofenac P : Zephyer Pharmatec (Pvt) Ltd.

Presently Kempro is available in tablet Form.

Kempro Tablet : Procyclidine HCl 5mg strength.

Kempro has several contraindications, which means that it should not be used in certain circumstances or by certain individuals. Here are some of the main contraindications of Kempro:

Allergy or Hypersensitivity: Individuals who have a known allergy or hypersensitivity to Kempro or any of its ingredients should not take this medication.

Glaucoma: Kempro can increase the pressure inside the eye, which can be dangerous for individuals with glaucoma, a condition that causes increased pressure in the eye. Kempro should be avoided in individuals with narrow-angle or closed-angle glaucoma.

Gastrointestinal Obstruction: Kempro can cause constipation, which can be dangerous in individuals with gastrointestinal obstruction, a blockage in the digestive tract. Kempro should be avoided in individuals with this condition.

Urinary Retention: Kempro can cause urinary retention, which is the inability to empty the bladder completely. This can be dangerous in individuals with a history of urinary retention, and Kempro should be avoided in these individuals.

Cardiac Conditions: Kempro can cause cardiac arrhythmias, or abnormal heart rhythms, in some individuals. It should be used with caution in individuals with a history of cardiac arrhythmias or other cardiac conditions.

Pregnancy and Breastfeeding: There is limited information on the safety of Kempro during pregnancy and breastfeeding, and it should be used with caution in these populations.

It is important to discuss any contraindications or concerns with a healthcare provider before taking Kempro.

The daily recommended dose of Kempro can vary depending on the condition being treated, the age and weight of the patient, and other individual factors. Therefore, it is important to follow the dosage instructions provided by a healthcare professional.

In general, the starting dose for adults is usually One Tablet (5mg) three times daily, which can be increased gradually as needed up to a maximum daily dose of 6 tablets (30mg) in 24 hours.

It is important to follow the prescribed dosing schedule and not exceed the recommended dose without the advice of a healthcare professional. Overdose of Kempro can lead to serious side effects, including confusion, agitation, hallucinations, seizures, and coma.

The mode of action of Kempro involves its ability to block the action of acetylcholine, a neurotransmitter in the brain and other parts of the body. Kempro is an anticholinergic medication that works by binding to and blocking the muscarinic acetylcholine receptors, which are found in many organs and tissues throughout the body.

By blocking these receptors, Kempro can help to reduce the effects of excessive cholinergic activity in the body, such as muscle rigidity, tremors, and involuntary movements, which are common symptoms of certain neurological disorders like Parkinson’s disease.

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