Liometacin injections must be made slowly, penetrating deep into the muscle of the upper external quadrant of the buttocks observing strict sterilization, aseptic and antiseptic standards.
During treatment, especially if prolonged, liver function and blood parameters should be checked regularly Patients must be warned to strictly observe the dosage prescribed by the physician to avoid serious adverse reactions which might occur if this dose is increased.
As indomethacin can cause a sensation of confusion, vertigo and headache in some patients, this should be brought to the attention of all those who may drive any kind of vehicle or carry out operations which require particular vigilance.
Parenteral administration may at times lead to a slight, brief hypotensive state. This drug cannot be considered a simple analgesic and must be used under strict medical supervision. Moreover, once the acute painful episode has passed, it is advisable to change to non-parenteral preparations, which although they may induce the same type of side effects, are less likely to cause severe reactions. Prolonged use of Liometacen is allowed only in hospitals or clinics.
