Tirlor Side Effects

Tirlor (Loratadine) has no clinically significant sedative or anti-cholinergic properties since fatigue, sedation, headache, nausea and dry mouth were rarely reported.

The following adverse events have been reported in at least one patient in Loratadine clinical trials: Autonomic nervous system, body as a whole, cardiovascular system, central and peripheral nervous system, gastrointestinol system, musculoskeletal system, phychiatric, reproductive system, respiratory system, skin and appendages, and urinary system.

Drug Interactions

Loratadine does not potentiate the effects of alcohol. Anti-histamines should be discontinued about 4 days prior to skin testing procedures, since these drugs may prevent or diminish otherwise positive to dermal reactivity indicators.

Over Dosage

In adults, somnolence, tachycardia, and headache have been reported with overdoses- greater than 10 mg. In the event of over dosage, general symptomatic and supportive measures should be instituted promptly and maintained for as long as necessary.

Contraindications

Loratadine is contraindicated in patients who have shown hypersensitivity or idiosyncrasy to any of its components.

Loratadine should be prescribed with caution in pregnancy and lactation since its safety is not established in such conditions.

Precautions

General: Patients with liver impairment or renal insufficiency (GFR <30ml/min) should be given a lower initial dose 10mg every other day.