Winurina Adverse Effects
Most commonly occuring adverse reactions with the usage of Winurina are; dizziness, somnolence, ataxia, headache, nystagmus, tremor, fatigue, diplopia, nausea, vomiting and rhinitis).
Drug Interations
Gabapentin is not appreciably metabolized nor does it interfere with the metabolism of commonly Co-administered antiepileptic drugs. Antacids containing magnesium and aluminium reduce Gabapentin bioavailability almost by 24%, so it is recommended to use Gabapentin at least after two hours following antacid administration.
Over Dosage
No specific information is available on the treatment of overdose with Gabapentin, although hemodialysis has been shown to be effective in eliminating Gabapentin. Treatment is symptomatic and supportive, consistent with established medical care. Overdose of Gabapentin up to 49g ingested at one time have been reported in four people, a 1 of whom recovered fullv. Symptoms of overdose included dizziness, double vision, slurred speech, drowsness ietnargv and mild diarrhea. In patients with renal impairment hemodialysis may be ndicated. Reduced absorption of Gabapentin at higher dose may limit drug absorption and hence minimize toxicitv at the time of overdosing.
