Description
Bic (Bisglycinate) is an extra gentle form of iron which is easily absorbed and does not irritate the stomach or digestive system. Iron is most important mineral involved in the formation of healthy red blood cells. It helps carry vital oxygen and nutrients to all parts of the body and may help to maintain normal metabolic functions as well as a feeling of strength, vigor, and vitality. BIC (Iron Bisglycinate) is a specially chelated formulation that is gentle on the stomach and does not cause irritation, constipation or diarrhea. Added to the formulation is Vitamin C, which helps faster absorption and assimilation of Iron from the stomach into the blood stream making it one of the most effective ways of taking iron supplements.
Mechanism of Action
Atomic structure of BIC protects ferrous from undesirable chemical reactions in the stomach and intestine that limits iron absorption. BIC molecule disguised as amino acid hence is rapidly absorbed by the mucosal cells of intestine. The stability constant of BIC is such adjusted that it is dissociated into individual components i.e iron and amino acid, after reaching into the mucosal cells, amino acids is thus used for nutritional purpose and iron adopts the regulatory pathways of metal. BIC is independent of pH change throughout the G.I. tract and remains soluble at acidic pH as well as alkaline pH. In this way BIC avails the maximum portion of small intestine for absorption, like the amino acids and provide 75% absorption rate.
Therapeutic Indications:
BIC is indicated for,Iron deficiency anemia due to insufficient intake of iron or impaired absorption, acute and chronic blood loss due to infection in patients of all ages,pregnancy, breast feeding.
Dosage & Administration
For Capsule
The recommended dose of BIC is one Capsule daily or directed the physician
For Syrup
Each 5 ml contains 130 mg of ferrous bisglycinate equivalent to 26 mg elemental iron irrespective of the meals. Adults one tea spoon daily or as directed by the physician. Children 1/2 to 1 tea spoon daily or as directed by the physician.
Contraindications
BIC is contraindicated in patients with known hyperse -nsitivity to any of its ingredients, haemosiderosis, haemochromatosis, aplastic and hemolytic anemia, lever cirrhosis.
Adverse Reactions
Very rare adverse reactions have been reported with BIC such as gastro intestinal disorders including diarrhea, nausea and epigastric pain may occasio -nally occur, especially when too high dosage is administered.
Interactions
Do not take iron supplements by mouth if you are also receiving iron injections.
Iron derivatives may impair the absorption of phenytoin, or antibiotics such as demeclocycline, doxycycline or tetracycline.
Tell your doctor if you are using antacids.