Solifen Side Effects

Solifen is a medication used to treat overactive bladder, a condition characterized by symptoms such as frequent urination, urgency, and incontinence. Like any medication, Solifen can have side effects. Here are some common and less common side effects of Solifen may include:

Common Side Effects

• Dry mouth: This is one of the most frequently reported side effects of Solifen. It can be helpful to stay hydrated by drinking water or sucking on ice chips.
• Constipation: Solifen may slow down the movement of the digestive tract, leading to constipation. Eating a diet high in fiber and drinking plenty of fluids can help alleviate this side effect.
• Blurred vision: Some people may experience visual disturbances, such as blurred vision while taking Solifen. If this occurs, it’s advisable to avoid activities that require clear vision, such as driving, until the effect subsides.
• Dry eyes: Solifen can reduce tear production, leading to dry eyes. Using artificial tears may provide relief.
• Upset stomach or indigestion: Some individuals may experience gastrointestinal discomfort, nausea, or indigestion while taking Solifen.
• Urinary retention: In rare cases, Solifen may cause difficulty emptying the bladder. If you experience trouble urinating or a decrease in the amount of urine, it’s essential to seek medical attention promptly.
• Headache: Headaches can occur as a side effect of Solifen.

Less Common Side Effects

• Dizziness or lightheadedness: Some people may feel dizzy or lightheaded while taking Solifen, especially when standing up quickly. It’s advisable to stand up slowly from a sitting or lying position to minimize this effect.
• Fatigue: A feeling of tiredness or fatigue may occur in some individuals.
• Allergic reactions: Although rare, some people may experience allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek medical attention promptly if you suspect an allergic reaction.
• Chest pain or palpitations: In rare cases, Solifen may cause chest pain or palpitations. If you experience any unusual heart-related symptoms, consult your healthcare provider.
• Confusion or hallucinations: Some individuals may experience confusion or hallucinations. This is more common in elderly patients.
• Difficulty sleeping (insomnia): Sleep disturbances may occur in some individuals while taking Solifen.
• Increased sensitivity to sunlight: Solifen may increase sensitivity to sunlight, making individuals more prone to sunburn. It’s advisable to use sunscreen and protective clothing when exposed to sunlight.
• Elevated heart rate (tachycardia): In rare instances, Solifen may cause an increased heart rate.

Solifen is one of the leading brands of Solifenacin Succinate, manufactured and marketed by Getz Pharmaceuticals (Pvt) Ltd, Pakistan.

Presently, Solifen is available in tablet form.

Solifen Tablets : 5mg and 10mg strengths.

1. Antimuscarinic drugs: Concurrent use of multiple antimuscarinic medications may increase the risk of side effects such as dry mouth, constipation, blurred vision, and urinary retention.
2. Potassium chloride supplements or medications that increase potassium levels: Solifen may increase the risk of urinary retention, and combining it with medications that affect electrolyte balance, such as potassium supplements or certain diuretics, could potentially exacerbate this risk.
3. Certain antibiotics: Some antibiotics, like clarithromycin and erythromycin, can increase the levels of Solifen in the blood, potentially leading to an increased risk of side effects.
4. Certain antifungal medications: Azole antifungals, such as ketoconazole and itraconazole, may also increase Solifen levels and the risk of side effects.
5. Certain HIV medications: Protease inhibitors used in the treatment of HIV, such as ritonavir, may interact with Solifen.
6. Medications that affect the heart rhythm: Solifen may interact with drugs that affect the QT interval, potentially leading to an increased risk of abnormal heart rhythms.
7. CYP3A4 inhibitors and inducers: Solifen is metabolized by the CYP3A4 enzyme. Drugs that inhibit or induce this enzyme may affect Solifen levels. Examples include certain antifungals, antibiotics, and medications used for the treatment of HIV.