Loprin (Aspirin) Drug Warnings

Important Information about Aspirin

Caution should be exercised in patients with allergic disease, impairment of hepatic or renal function (avoid if severe) and dehydration. Loprin (aspirin) may also precipitate bronchospasm or induce attacks of asthma in susceptible subjects. The elderly may be more susceptible to the toxic effects of salicylates. Continuous prolonged use of Loprin (aspirin) should be avoided in the elderly because of the risk of gastrointestinal bleeding. Caution should be taken in patients with glucose-6-phosphate dehydrogenase deficiency as haemolytic anaemia may occur. Aspirin may interfere with insulin and glucagon in diabetes. Aspirin prolongs bleeding time, mainly by inhibiting platelet aggregation and therefore it should be discontinued several days before scheduled surgical procedures. Haematological & haemorrhagic effects can occur, and may be severe. Patients should report any unusual bleeding symptoms to their physician. There is a possible association between aspirin and Reye's Syndrome when given to children. Reye's syndrome is a very rare disease, which affects the brain and liver, and can be fatal. For this reason aspirin should not be given to children aged under 16 years unless specifically indicated (e.g. for Kawasaki's disease). Salicylates should not be used in patients with a history of coagulation abnormalities as they may also induce gastro-intestinal haemorrhage, occasionally major. Aspirin should not be taken by patients with a stomach ulcer or a history of stomach ulcers. Before commencing long term aspirin therapy for the management of cardiovascular or cerebrovascular disease patients should consult their doctor who can advise on the relative benefits versus the risks for the individual patient. Patients with hypertension should be carefully monitored.

Related Links

Free Prescription Drugs Information by Dr.Thomas Williams