Nexum Tablet Uses

Nexum is a proton pump inhibitor medication that is used to relieve symptoms of gastroesophageal reflux disease and other conditions caused by excess stomach acid. Nexum has anti-acid properties which can help to prevent tissue damage by excess amounts of stomach acid production. Following are some common uses of Nexum:

1. Gastroesophageal Reflux Disease (GERD): Nexum is often prescribed to individuals suffering from GERD. It helps alleviate symptoms like heartburn, acid regurgitation, and difficulty swallowing.
2. Peptic Ulcers: Nexum is used in the treatment of peptic ulcers, which are open sores that develop on the lining of the stomach or the upper part of the small intestine. It helps in healing existing ulcers and preventing new ones.
3. Erosive Esophagitis: Nexum is used to treat erosive esophagitis, a condition characterized by severe irritation and inflammation of the lining of the esophagus.
4. Zollinger-Ellison Syndrome: Nexum is also used for rare conditions like Zollinger-Ellison syndrome, where the stomach produces excessive amounts of acid.
5. Helicobacter pylori Infection: Nexum is sometimes used in combination with antibiotics to treat infections caused by the bacterium Helicobacter pylori, which can lead to conditions like gastritis and peptic ulcers.
6. Prevention of Stomach Ulcers: For individuals taking non-steroidal anti-inflammatory drugs (NSAIDs) long-term, Nexum may be used to help prevent the development of ulcers.
7. Reflux Esophagitis: Nexum can be used to treat reflux esophagitis, which is inflammation of the esophagus due to the backflow of stomach acid.
8. Stomach Acid-Related Disorders: Nexum is used to manage various conditions related to excessive stomach acid production, such as relief from heartburn and indigestion.

Off-Label Uses of Nexum

1. Barrett’s Esophagus: This is a condition where the lining of the esophagus changes, potentially leading to esophageal cancer. Nexum may be used as part of a treatment plan.
2. Aspiration Pneumonia: In some cases, Nexum may be considered as part of a treatment plan for aspiration pneumonia, a condition where foreign material is breathed into the lungs.
3. Gastric Motility Disorders: Nexum may be used off-label to help manage certain disorders affecting the movement of the stomach.
4. Gastrinoma: Also known as a gastrin-secreting tumor, Nexum may be considered as part of a treatment plan for this rare condition.
5. Stress Ulcer Prophylaxis: In some cases, especially in intensive care settings, Nexum may be used to prevent stress-related ulcers in critically ill patients.
6. Pernicious Anemia: Nexum can also be used in adjunctive therapy as an alternative drug of choice in Pernicious anemia and other macrocytic anemias.

It’s also important to note that while PPIs like Nexum can be beneficial for some people with heartburn symptoms related to GERD and other digestive issues, they do not cure these conditions – they only treat them temporarily until the underlying cause is addressed through lifestyle changes and/or other treatments prescribed by a doctor.

Nexum is one of the leading brands of Esomeprazole, manufactured and marketed by Getz Pharma Pakistan.

The following are some available alternative brands of Nexum.

• Esso : Shaigan Pharmaceuticals (Pvt) Ltd, Pakistan.
• NovoTeph : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.
• Contour : Continental Pharmaceuticals (Pvt) Ltd, Pakistan.
• Ezium : Searl Pakistan.
• Eskem : High Q Pharmaceuticals (Pvt) Ltd, Pakistan.
• Ezomol : Abbott Laboratories, Pakistan.
• Esorid : Hilton Pharmaceuticals (Pvt) Ltd, Pakistan.
• Esofil : Saffron Pharmaceuticals (Pvt) Ltd, Pakistan.
• Esante : Macter International.
• Esomega : Ferozesons Laboratories Ltd.

Presently, Nexum is available in Capsules Form

Nexum Capsules : 20mg and 40mg Strengths

There are some important contraindications that should be considered before using Nexum tablet.

People should not use Nexum who have a known allergy to it or any other PPI drugs.

People should not use Nexum who are taking HIV medications such as saquinavir.

People should not use Nexum who have had low magnesium levels in the past.

Pregnant or breastfeeding women should not use Nexum without consulting a doctor about the safety of this medication.

People who have had liver problems in the past should use extreme caution when considering using Nexum since it has been linked to further liver damage in some cases.

It’s important to speak with a doctor before starting any new medications so that they can assess whether using Nexum is right.

The usual dose for adults (18 years old or older): 20mg to 40mg once daily before breakfast for up to 8 weeks.

However, some patients may require higher dosages for longer periods of time based on their specific condition.

The active ingredient found within Nexum binds specifically onto proton pumps located inside cells lining our digestive tracts known as parietal cells which produce hydrochloric acids. Reducing the amount these pumps release thus decreasing the total concentration of acidic environment overall helps restore the normal pH balance needed to prevent further damage from occurring surrounding tissues and organ systems.

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