Methycobal tablet is used to treat anemia and deficiencies in vitamin B12 levels, as well as other neurological disorders. Following are some common and off-label uses of Methycobal tablets:

Common Uses of Methycobal Tablet

  1. Anemia: Methycobal tablet is used to treat anemia caused by vitamin B12 deficiency. Vitamin B12 is necessary for the production of red blood cells, and a deficiency can lead to anemia.
  2. Nerve Disorders: Methycobal tablet is used to treat and prevent nerve disorders, such as peripheral neuropathy, which can occur as a result of vitamin B12 deficiency. Methycobal helps to protect and regenerate nerves, which can alleviate symptoms such as numbness, tingling, and pain.
  3. Cognitive Function: Methycobal tablet is used to improve cognitive function, especially in older adults who may be at risk for vitamin B12 deficiency. It helps improve memory, concentration, and overall cognitive performance.
  4. Fatigue and Weakness: Methycobal tablet is used to alleviate fatigue and weakness caused by vitamin B12 deficiency. Vitamin B12 is essential for energy production, and a deficiency can lead to fatigue and weakness.
  5. Depression: Methycobal tablet is used as an adjunct therapy in the treatment of depression, especially in individuals who have a vitamin B12 deficiency. Vitamin B12 is involved in the production of neurotransmitters such as serotonin and dopamine, which are important for regulating mood.
  6. Cardiovascular Health: Methycobal tablet is used to reduce the risk of cardiovascular disease, as vitamin B12 deficiency has been associated with an increased risk of heart disease. It helps reduce levels of homocysteine, an amino acid that has been linked to cardiovascular disease.

Off-label Uses of Methycobal Tablet

  1. Diabetic Neuropathy: Methycobal tablets may be effective in treating diabetic neuropathy, which is a type of nerve damage that can occur in people with diabetes. It helps to protect nerves from damage and promote nerve regeneration, which can alleviate symptoms such as pain and numbness.
  2. Multiple Sclerosis: Methycobal tablets may be beneficial in the treatment of multiple sclerosis (MS), a chronic autoimmune disease that affects the nervous system. It helps to protect and regenerate nerves, which can improve symptoms such as muscle weakness, tremors, and fatigue.
  3. Tinnitus: Tinnitus is a condition characterized by ringing or buzzing in the ears. Methycobal tablets may be effective in reducing the severity of tinnitus and improving hearing function.
Methycobal Uses and Indications

What is Methycobal?

Methycobal is one of the leading brands of Mecobalamin, manufactured and marketed by Hilton Pharmaceuticals, Pakistan.

Methycobal Tablet’s Alternatives : Other Similar Brands

The following are some alternative brands of Methycobal and their manufacturers.

  • Cobolmin : Mecter International, Pakistan.
  • Neuromet : Merck Serono Pharmaceutical.
  • Mecobal : NabiQasim Pharmaceuticals, Pakistan.
  • Mabil : Sami Pharmaceuticals, Pakistan.
  • Nervon : Getz Pharmaceuticals, Pakistan.
  • Mecogen : Genetics Pharmaceuticals, Pakistan.
  • Qbal : Bosch Pharmaceuticals, Pakistan
  • Bezel : Saffron Pharmaceuticals, Pakistan.
  • Incobal : Indus Pharmaceuticals, Pakistan.
  • Elgin : Novartis, Pakistan.
  • Mylaxzon : Barrett Hodgson Pharmaceuticals, Pakistan.

Methycobal : Available Formulations and Strengths

Presently, Methycobal is available in Tablet and Injection forms

Methycobal Tablet : 500mcg strength

Methycobal Injection : 500mcg/ml strength

Who Should Not Use Methycobal?

It is important for individuals to speak with their doctor first before starting a regimen of tMethycobal tablet due to certain contraindications of its use, which include:

  • Pregnancy or nursing mothers
  • Individuals sensitive or allergic to cobalt
  • Those with kidney disease
  • People taking anticoagulants such as warfarin (Coumadin)
  • Those suffering from Leber’s disease
  • Individuals over 65 years old who have had long-term exposure or ingestion of large amounts of cobalt
  • People who are at risk for developing heart problems due to excessive intake of Vitamin B12 supplements (more than 1000mcg/day)

In these cases, alternative treatments may need to be considered instead of Methycobal supplementation therapy.

What is the Recommended Daily Dosage of Methycobal Tablet?

Methycobal Tablet Dose for Vitamin B12 Deficiency:

  • 1 – 3 tablets of 500mcg per day.
  • The specific dosage will depend on the severity of the deficiency and the healthcare provider’s assessment.

Methycobal Tablet Dose for Pernicious Anemia:

  • 2 – 4 tablets of 500mcg per day
  • Or directed by the healthcare provider.

Methycobal Tablet Dose for Neuropathy Associated with B12 Deficiency:

  • 1 – 3 tablets of 500mcg per day.
  • Depending on the severity of symptoms and the healthcare provider’s recommendation.

Methycobal Tablet Dose for Nerve Disorders: 

  • 1 – 2 tablets, three times a day.

Methycobal Tablet Dose for Cognitive Function:

  • 1 – 2 tablets of 500mcg per day.

How Methycobal Works?

Methycobal is a centrally-acting drug, and it is a synthetic form of vitamin B12. Methycobal works by stimulating the formation of a compound called myelin, which is known as the protection cover of nerves.

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Methycobal Side Effects