Flexin Tablet Uses

Flexin tablet is a nonsteroidal anti-inflammatory drug that is used to relieve pain, inflammation, and fever. Following are some common uses of Flexin Tablets:

1. Arthritis: Flexin tablet is used for the treatment of arthritis, a condition that causes inflammation and pain in the joints. There are several types of arthritis, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. It helps reduce joint pain, stiffness, and swelling associated with arthritis, making it easier for patients to move and perform daily activities.
2. Menstrual Cramps: Flexin tablets can be used to treat the pain and discomfort associated with menstrual cramps.
3. Headaches: Flexin tablet is effective in treating headaches, including tension headaches and migraines. It can be used as a preventive measure or as needed to alleviate symptoms.
4. Gout: Flexin tablets can help reduce the pain and inflammation associated with gout, a type of arthritis caused by the buildup of uric acid crystals in the joints. It helps to reduce the production of uric acid, which can help prevent future gout attacks.
5. Tendonitis and Bursitis: Flexin tablet is sometimes used to treat tendonitis and bursitis, which are conditions that cause inflammation in the tendons and bursae (small fluid-filled sacs that cushion the joints). By reducing inflammation, it relieves pain and stiffness in affected areas.
6. Dental Pain: Flexin tablets can be used to treat dental pain, such as toothaches and post-surgical pain.
7. Fever: Flexin tablet can also be used to reduce fever, as it helps to lower the body’s temperature by reducing inflammation.

Off-label Uses of Flexin Tablet

1. Paget’s disease of bone: Paget’s disease of bone is a condition in which the bones become abnormally thick, fragile, and misshapen.
2. Bartter syndrome: Bartter syndrome is a rare genetic condition that affects the kidneys’ ability to absorb potassium.
3. Cluster headaches: Cluster headaches are a type of severe headache that occurs in clusters.
4. Migraines: Migraines are severe headaches that are often accompanied by nausea, vomiting, and sensitivity to light and sound.
5. Fibromyalgia: Fibromyalgia is a chronic pain disorder that is characterized by widespread muscle pain and tenderness.
6. Cancer pain: Flexin tablets may be used to treat mild to moderate cancer pain.

Flexin is one of the leading brands of Naproxen, manufactured and marketed by Abbott Laboratories Pakistan.

Following are some alternative brands of Flexin and their manufacturers.

• Synflex : Martin Dow Pakistan.
• Dolonap : Platinum Pharmaceuticals, Pakistan.
• Neoprox : Martin Dow Pharmaceuticals, Pakistan.
• Anex : Pharmevo (Pvt) Ltd, Pakistan.
• Napreben : Pacific Pharmaceuticals, Pakistan.
• Apranax : Roache Pakistan Ltd.
• Genoxen : Genix Pharmaceuticals, Pakistan.
• Naplex : Global Pharmaceuticals, Pakistan.
• Aproxen : The Schazoo Laboratories, Pakistan.
• Dephalog : Standpharm, Pakistan (Pvt) Ltd.

Presently, Flexin is available in Tablet Form.

Flexin Tablets : 250mg and 500mg strengths.

Despite its many uses, there are some situations in which Flexin should be avoided or used with caution. Some of the most important contraindications of Flexin are:

Allergies: People who are allergic to Flexin or other NSAIDs should not take Flexin.
Ulcers: Flexin can increase the risk of stomach ulcers and gastrointestinal bleeding, so it should be used with caution in people with a history of ulcers or other gastrointestinal problems.
Heart disease: Flexin can increase the risk of heart attack and stroke, especially in people with preexisting heart disease or risk factors for heart disease.
Pregnancy: Flexin should not be used during pregnancy, especially in the third trimester, as it can harm the developing fetus.
Breastfeeding: Flexin can pass into breast milk and may harm a nursing infant, so it should be used with caution while breastfeeding.
Liver and kidney disease: Flexin can be harmful to people with liver or kidney disease, so it should be used with caution in these patients.

The recommended daily dose of Flexin can vary depending on the condition being treated and the patient’s age and overall health. Here are some general guidelines for recommended doses of Flexin:

For adults with mild to moderate pain or fever: The recommended dose is 250 to 500 mg every 8 to 12 hours as needed, not to exceed 750 mg in a 24-hour period.

For adults with osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis: The recommended starting dose is 500 mg, followed by 250 mg every 6 to 8 hours or 375 mg every 12 hours as needed. The maximum daily dose should not exceed 1250 mg.

For adults with gout: The recommended dose is 750 mg, followed by 250 mg every 8 hours until the attack has subsided.

For children: The recommended dose of Flexin for children depends on their age and weight. It is typically given at a dose of 5 to 10 mg per kilogram of body weight every 8 to 12 hours as needed.

Additionally, the dosage and frequency of Flexin may need to be adjusted for patients with liver or kidney disease or those who are taking other medications that may interact with Flexin.

Flexin works by inhibiting both COX-1 and COX-2 enzymes, which reduces the production of prostaglandins throughout the body. By blocking the production of prostaglandins, Flexin helps to reduce inflammation, relieve pain, and lower fever.

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