Epival Tablet Uses

Epival tablet is primarily used for the treatment of epilepsy (seizures) and other mental illnesses. It belongs to the class of drugs known as anticonvulsant (anti-epileptic) medication. Epival tablets are commonly used for the following indications:

1. Epilepsy: Epival tablet is commonly used for the treatment of various types of seizures in people with epilepsy. It can help reduce the frequency and severity of seizures by stabilizing electrical activity in the brain.
2. Bipolar Disorder: Epival tablet is also used as a mood stabilizer in the management of bipolar disorder. It helps to control manic episodes and prevent the recurrence of both manic and depressive episodes, promoting more stable moods and reducing the intensity of mood swings.
3. Migraine Prophylaxis: Epival tablets may also be used for the prevention of migraine headaches in adults. It is effective in reducing the frequency, duration, and intensity of migraine attacks when taken regularly.

Off-label Uses of Epival Tablet

1. Agitation and Behavioral Disorders: Epival tablet is sometimes used off-label to manage agitation and behavioral symptoms associated with various conditions, including dementia, autism spectrum disorder, and intellectual disabilities. It can help stabilize mood, reduce irritability, and manage aggressive or impulsive behaviors.
2. Anxiety Disorders: Epival tablets may be used as an adjunctive treatment for certain anxiety disorders, such as generalized anxiety disorder and social anxiety disorder. It may help to reduce anxiety symptoms and promote emotional stability in some individuals.
3. Post-Traumatic Stress Disorder (PTSD): Epival tablet has been explored as an off-label use for PTSD. It may be considered in cases where other treatment options have been ineffective or not well-tolerated.
4. Other Seizures: Epival tablets may also be used off-label for other seizure disorders such as absence seizures and infantile spasms.

Epival is one of the leading brands of Divalproex sodium, manufactured and marketed by Abbott Pharma Pakistan.

Here are Some Alternative Brands of Epival and Their Manufacturers.

• Dapakan : Platinum Pharmaceuticals (Pvt) Ltd.
• Epilim Chrono : Searle Pakistan (Pvt) Ltd.
• Leptil : Don Valley Pharmaceuticals (Pvt) Ltd.
• Prizm : PharmEvo (Pvt) Ltd.
• Revalp : Genetics Pharmaceuticals (Pvt) Ltd.
• Valep : Geofman Pharmaceuticals (Pvt) Ltd.
• Valpro : Don Valley Pharmaceuticals (Pvt) Ltd.
• Epilim : Sanofi Aventis Pakistan Ltd.
• Epirate : Wilsons Pharmaceuticals.
• Valtec : Geofman Pharmaceuticals (Pvt) Ltd.

Presently, Epival is available in Tablet, Injection, and Syrup Forms

Epival Tablets : 250mg and 500mg Strengths

Epival Syrup : 250mg/5ml

Epival Injection : 500mg/5ml

Epival should not be used if you have any allergies or medical conditions such as kidney disease, liver problems, pancreas problems, or a history of depression or suicidal thoughts.

Additionally, it should not be taken by pregnant women due to potential risks associated with its use during pregnancy and breastfeeding; those trying to become pregnant should also speak with their doctor before using this drug.

Furthermore, patients taking other medications that interact with Epival (such as aspirin) may need close monitoring from their physician while on these drugs together.

Dosing guidelines of Epival vary depending on the condition being treated and the individual’s response to therapy but generally range from 250mg twice daily to 1g twice daily divided into two doses (morning and evening).

The maximum dose should not exceed 60mg/kg per day unless specified by a doctor or pharmacist.

Epival works by stabilizing levels of neurotransmitters in the brain called gamma-aminobutyric acid (GABA) and glutamate (GLU). GABA helps reduce nerve activity while GLU helps increase it; when these two chemicals exist in balance they help maintain normal functioning within the nervous system thus reducing symptoms associated with epilepsy and bipolar disorder such as manic episodes and seizures. The exact way that Epival does this is still unclear but research has suggested that it affects certain receptors within cells that interact directly with both GABA and GLU resulting in an overall calming effect on neural activity which reduces symptoms associated with epilepsy or bipolar disorder when taken appropriately over time.

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