Coldrex Tablet Uses

Coldrex tablet is used to treat headaches, muscle and joint pain, inflamed nasal membranes, sinus pain, dry cough, sore throat, and painful swallowing. It provides short-term relief for flu, fever, cold, and cough.

Ingredients of Coldrex Tablets and Their Uses

Coldrex is a combination of three commonly used medications Paracetamol, Dextromethorphan, and Chlorpheniramine.

1. Relief of Pain and Fever: Paracetamol is a widely used analgesic (pain reliever) and antipyretic (fever reducer). It helps to alleviate pain, such as headaches, muscle aches, and sore throat and reduces fever commonly associated with colds and flu.
2. Cough Suppression: Dextromethorphan is a cough suppressant that helps alleviate coughing. It works by acting on the cough reflex in the brain, reducing the urge to cough. It is used to provide temporary relief from dry, non-productive coughs commonly associated with colds and respiratory infections.
3. Relief of Nasal Congestion and Allergic Symptoms: Chlorpheniramine is an antihistamine with anticholinergic properties. It helps alleviate symptoms of nasal congestion, runny nose, and sneezing caused by allergies or respiratory infections. Chlorpheniramine also helps relieve itching and watery eyes associated with allergic reactions.

Coldrex is one of the leading brands with a combination of Paracetamol, Dextromethorphan, and Chlorpheniramine, manufactured and marketed by Standpharm Pakistan (Pvt) Ltd.

Presently, Coldrex is available in Tablet and Syrup Forms

Coldrex Tablet : Paracetamol 325mg, Dextromethorphan 10mg, and Chlorpheniramine 1mg strengths

Coldrex Syrup : Paracetamol 325mg/5ml, Dextromethorphan 15mg/5ml, and Chlorpheniramine 1mg/5ml strengths

Although Colder is an effective and safe drug, still there are some contraindications associated with this drug or its ingredient.

The people with following conditions should not use Coldrex:

People who are allergic to any of its active ingredient Paracetamol, Dextromethorphan, and Chlorpheniramine.

People who suffer from hypertension (blood pressure), cardiovascular problems, or severe ischemic heart disease.

People who have hyperthyroidism (overactive thyroid gland).

People who have diabetes.

People who have glaucoma (elevated eye pressure).

People who have adrenal tumors (pheochromocytoma).

People who have liver damage or compromised kidney.

People who are taking other decongestants.

People who are taking tricyclic antidepressants.

People who are taking beta-blockers.

People who are taking or have taken antidepressants called monoamine oxidase (MAO) inhibitors in the last two weeks.

Pregnant or lactating women.

Coldrex Tablet in Adults: 2 Tablets every 4 to 6 hours, the maximum dose is 8 tablets in a day

Coldrex Tablet in Children (6 to 12 Years): 1 to 1.5 Tablets every 4 to 6 hours, the maximum dose is 4 tablets in a day

Coldrex Syrup in Children (6 to 12 Years): 0.5 to 1 teaspoon every 4 to 6 hours, the maximum dose is 9 teaspoons a day

Coldrex Syrup in Children (2 to 6 Years): 1 teaspoon every 4 to 6 hours, the maximum dose is 4 teaspoons a day

Each component of Coldrex has a distinct mode of action:

1. Paracetamol (an active ingredient of Coldrex) works by inhibiting the production of certain chemicals in the body that contribute to pain and fever. It blocks the production of prostaglandins, which are involved in the inflammatory response and pain signaling pathways.
2. Dextromethorphan (another active ingredient of Coldrex) works by suppressing the cough reflex, reducing the urge to cough. It does not directly target the underlying cause of the cough but provides temporary relief from the cough.
3. Chlorpheniramine (also another active ingredient of Coldrex) blocks the effects of histamine, a chemical released during allergic reactions. By blocking histamine receptors, chlorpheniramine helps to alleviate symptoms of allergies or respiratory infections.

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Coldrex Side Effects