Celbex tablet is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used to reduce pain and inflammation. Following are some common and off-label uses of Celbex tablets:

Common Uses of Celbex Tablet

  1. Osteoarthritis: Celbex can help relieve the pain and inflammation associated with osteoarthritis, a type of arthritis that affects the joints.
  2. Rheumatoid Arthritis: Celbex tablets can also be used to treat rheumatoid arthritis, an autoimmune disease that causes joint pain, stiffness, and swelling.
  3. Ankylosing Spondylitis: This is a type of arthritis that affects the spine, and the use of Celbex tablet in such a condition can help relieve the pain and inflammation.
  4. Menstrual Cramps: Celbex can also be used to treat menstrual cramps, a common condition in women.
  5. Acute Pain: Celbex can be used to manage acute pain caused by various conditions such as dental procedures, surgeries, and injuries.
  6. Familial Adenomatous Polyposis (FAP): Celbex is also used to treat FAP, a rare inherited condition that causes multiple polyps in the colon and rectum.
  7. Migraine Headaches: Celbex can be used to relieve acute migraine headaches in adults.

Off-label Uses of Celbex Tablet

  1. Acute Gout: Celbex tablets may be used to manage acute gout attacks when other NSAIDs are not suitable due to underlying health conditions.
  2. Cancer Prevention: Celbex tablets may be used off-label to prevent colorectal cancer in individuals with certain risk factors or genetic predispositions.
  3. Neuropathic Pain: In some cases, Celbex tablets may be considered for neuropathic pain conditions, although it is not a first-line treatment for this type of pain.
  4. Inflammatory Skin Conditions: Celbex tablets may be used in some cases of inflammatory skin conditions where inflammation and pain are significant factors.
  5. Alzheimer’s Disease: Celbex tablet can be used in the treatment of Alzheimer’s disease, based on its anti-inflammatory properties.

Major Benefit of Using Celbex Tablet:

The primary benefit of using Celbex tablets over other NSAIDs is its ability to provide relief without causing serious gastrointestinal side effects such as ulcers or bleeding that may occur with long-term use of other NSAIDs.

Celbex Uses and Indications

What is Celbex?

Celbex is one of the leading brands of Celecoxib, manufactured and marketed by Getz Pharmaceuticals, Pakistan.

Celbex : Available Formulations and Strengths

Presently, Celbex is available in Capsules form

Celbex Capsules : 100mg, and 200mg strengths

Celbex Plus Capsule : 400mg strength

Who Should Not Use Celbex?

Despite the potential benefits of Celbex tablet uses discussed above, there are several contraindications that must be taken into consideration before beginning a course of treatment:

  • Celbex should not be taken by people who have had allergic reactions to sulpha drugs or aspirin-like medications in the past, due to an increased risk of developing serious side effects from taking these medications together.
  • Individuals who have had coronary artery bypass graft surgery should not use Celbex as it can increase their risk of developing heart problems or stroke in some cases.
  • Pregnant women should avoid using Celbex unless recommended by their doctor due to potential risks for both mother and baby during pregnancy or breastfeeding periods if taken at high doses for extended periods of time.

What is the Recommended Daily Dosage of Celbex?

Celbex Tablet Dose for Acute Pain or Pain During Menstruation:

  • Adults Dosage: One tablet of 200mg twice daily.

Celbex Tablet Dose for Ankylosing Spondylitis or Osteoarthritis:

  • Adults Dosage: One tablet of 200mg once daily

Celbex Tablet Dose for Rheumatoid Arthritis or Juvenile Rheumatoid Arthritis:

  • Adults Dosage: 100 to 200 mg 2 times a day

Note: Children’s dose is based on body weight and must be prescribed by a healthcare professional.

How Celbex Works?

A Celbex tablet provides anti-inflammatory, analgesic, and antipyretic activities. Celbex works on the prevention of prostaglandin synthesis by the inhibition of cyclooxygenase 2 (COX-2). Celbex is a selective COX inhibitor, it does not inhibit the cyclooxygenase-1 (COX-1) isoenzyme.

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