Brotin Tablet Uses

Brotin tablet is primarily used to alleviate symptoms associated with certain endocrine problems. It belongs to a class of medications known as dopamine agonists. Brotin tablets are commonly used for the following indications:

1. Hyperprolactinemia: Brotin tablet is commonly used to treat conditions characterized by elevated levels of prolactin hormone, a condition known as hyperprolactinemia. It helps reduce excessive prolactin production by the pituitary gland, which can cause symptoms like irregular menstrual periods, infertility, galactorrhea (milk production in non-lactating individuals), and decreased libido.
2. Acromegaly: Brotin tablets may be used as part of the treatment for acromegaly, a hormonal disorder characterized by excessive growth hormone production. It helps to lower growth hormone levels and reduce symptoms such as enlarged facial features, enlarged hands and feet, and joint pain.
3. Neuroleptic Malignant Syndrome (NMS): Brotin tablet is sometimes used in the management of neuroleptic malignant syndrome, a rare and potentially life-threatening condition that can occur as a severe reaction to certain medications used in the treatment of psychiatric disorders. It helps to regulate dopamine levels and improve symptoms such as muscle rigidity, high fever, altered mental status, and autonomic dysfunction.
4. Parkinson’s Disease: Brotin tablet is also used as an adjunct therapy in the treatment of Parkinson’s disease. It helps to reduce the symptoms of the condition, such as tremors, stiffness, and impaired movement, by increasing dopamine activity in the brain.

Off-label Uses of Brotin Tablet

1. Polycystic Ovary Syndrome (PCOS): Brotin tablet is sometimes used off-label to manage the hormonal imbalances associated with PCOS, including reducing elevated levels of prolactin and restoring normal ovulation.
2. Fibrocystic Breast Disease: Brotin tablets may be used to alleviate symptoms of breast pain and discomfort associated with fibrocystic breast disease.
3. Type 2 Diabetes: Brotin tablets may also help improve glycemic control and reduce insulin resistance in individuals with type 2 diabetes.
4. Non-functioning Pituitary Adenomas: Brotin tablets can be used in the management of non-functioning pituitary adenomas, which are benign tumors of the pituitary gland that do not produce excess hormones. It may help reduce tumor size and alleviate symptoms related to the mass effect on surrounding structures.

Brotin is one of the famous brands of Bromocriptine Mesylate, manufactured and marketed by Shaigan Pharmaceuticals, (pvt) Ltd, Pakistan.

Presently, Brotin is available in Tablet Form

Brotin Tablet : 2.5mg strength

It’s important to note that Brotin has several contraindications which must be taken into consideration before taking this medication:

• Pregnancy: Bromocriptine should not be used during pregnancy due to possible risk factors on fetal development;
• Cardiovascular diseases: Patients who have existing cardiovascular diseases should consult their doctor before taking this medication;
• Mental health issues: Patients who suffer from mental health issues such as depression or psychosis should avoid using this medication;
• Hypertension: Bromcripitne may increase blood pressure, so those suffering from hypertension should speak with their doctor before using it;
• Kidney disease: Those with kidney disease should not take this drug as it may worsen their condition further;
• Glaucoma: People suffering from glaucoma should avoid using bromcripitne due to its potential side effects on vision ;
• Breast cancer : Women diagnosed with breast cancer are advised against taking this drug as it could make tumor growth worse.

Brotin usual dose is to start with 1mg to 1.25mg at bed time, and increase the dose after 2 to 3 days as 2mg to 2.5mg at bed time.

Dose should not exceed 15mg/day

Brotin works by binding to dopamine receptors in the brain and blocking their activity. This reduces the amount of dopamine available in the body and helps to bring hormone levels back into balance.

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