Bromalex Tablet Uses

Bromalex tablet is primarily used for the treatment of anxiety disorders and related conditions. It belongs to the class of benzodiazepines. Following are some common uses of Bromalex Tablet:

1. Generalized Anxiety Disorder (GAD): Bromalex tablet is used for the management of generalized anxiety disorder, which is characterized by excessive and uncontrollable worry and anxiety about various aspects of life. It helps to reduce the symptoms of anxiety, such as restlessness, irritability, muscle tension, and difficulty concentrating.
2. Panic Disorder: Bromalex tablets may be used for the treatment of panic disorder, which involves recurrent and unexpected panic attacks accompanied by intense fear or discomfort. It can help alleviate symptoms during panic attacks and reduce the frequency and severity of panic episodes.
3. Social Anxiety Disorder: Bromalex tablets may be used to manage social anxiety disorder, also known as social phobia. It is characterized by intense fear and anxiety in social situations. Bromalex can help reduce anxiety symptoms and enable individuals to cope better with social interactions.
4. Insomnia Associated with Anxiety: Bromalex tablets may be used for short-term treatment of insomnia when it is associated with anxiety. It helps induce sleep and improve sleep quality.
5. Alcohol Withdrawal: Bromalex tablet is sometimes used to manage symptoms of alcohol withdrawal, particularly to prevent or treat alcohol withdrawal seizures. It helps to stabilize the central nervous system and reduce the risk of severe withdrawal symptoms.

Off-label Uses of Bromalex Tablet

1. Insomnia: While Bromalex tablet is used for the short-term treatment of insomnia associated with anxiety, it may also be used off-label for other types of insomnia. It can help induce sleep and improve sleep quality, but the risks and benefits should be carefully evaluated by a healthcare professional.
2. Muscle Spasms: Bromalex tablet’s muscle relaxant properties make it a potential option for managing muscle spasms, such as those caused by musculoskeletal injuries or conditions like fibromyalgia.
3. Premenstrual Syndrome (PMS): Bromalex tablets may be used off-label to alleviate anxiety and emotional symptoms associated with premenstrual syndrome (PMS).

Bromalex is one of the leading brands of Bromazepam, manufactured and marketed by Indus Pharma (Pvt) Ltd, Pakistan.

Here are some alternative brands of Bromalex and their manufacturers.

Lexotanil : Roche Pakistan, Ltd.

Relaxin : Macter Internation (Pvt) Ltd, Pakistan.

Brolite : Standpharm Pakistan (Pvt) Ltd.

Sambro : Sami Pharmaceuticals (Pvt) Ltd, Pakistan.

Anxit : Atco Laboratories Ltd, Pakistan.

Anzonil : Global Pharmaceuticals, Pakistan.

Brexxel : High-Q International.

Durazanil : Tabros Pharma.

E-ZE : Genix Pharma (Pvt) Ltd.

Freedom : Libra Pharmaceuticals (Pvt) Ltd.

Presently, Bromalex is available in Tablet Form with the following strength.

Bromalex Tablet : 3mg strength.

Bromalex has several contraindications, which are medical conditions or situations where the use of Bromalex is not recommended due to the potential risks outweighing the benefits.

1. Hypersensitivity: Bromalex is contraindicated in individuals with known hypersensitivity or allergy to Bromalex or other benzodiazepines. Allergic reactions to Bromalex can range from mild skin rashes to severe allergic reactions.
2. Severe Respiratory Insufficiency: Bromalex is contraindicated in individuals with severe respiratory insufficiency or respiratory failure. It can suppress respiratory function, and in individuals with compromised respiratory function, it may lead to further respiratory depression.
3. Sleep Apnea Syndrome: Bromalex is contraindicated in individuals with sleep apnea syndrome, a sleep disorder characterized by recurrent interruptions in breathing during sleep. Benzodiazepines can worsen respiratory function in individuals with this condition.
4. Severe Hepatic Impairment: Bromalex is contraindicated in individuals with severe hepatic impairment, as it may not be adequately metabolized and cleared from the body. This can increase the risk of Bromalex accumulation and potential adverse effects.
5. Myasthenia Gravis: Bromalex is contraindicated in individuals with myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue. Benzodiazepines can further weaken muscle function in individuals with this condition.
6. Acute Narrow-Angle Glaucoma: Bromalex is contraindicated in individuals with acute narrow-angle glaucoma, a type of glaucoma characterized by sudden increases in intraocular pressure. Benzodiazepines can increase intraocular pressure, which can worsen the condition.

Bromalex Dose for Anxiety Disorders:

• One Tablet of 3mg, two to three times per day.
• The dose may be adjusted based on the individual’s response and tolerance.
• The maximum recommended daily dose is typically 30 mg.

Bromalex Dose for Insomnia:

• Two Tablets of 3mg, before bedtime.
• The dose can be adjusted based on individual response and should not exceed 18 mg per day.

Bromalex works by binding to specific sites on the GABA receptors, known as benzodiazepine receptors. This binding enhances the affinity of GABA for its receptors and facilitates the opening of chloride ion channels. As a result, there is an increased influx of chloride ions into the neurons, leading to hyperpolarization and inhibition of neuronal activity.

By enhancing the inhibitory effects of GABA, Bromalex helps reduce excessive anxiety and promotes a sense of calm and relaxation.